Abstract No.:
3773

 Scheduled at:
Friday, May 23, 2014, Hall H3 1:40 PM
Medical Industry 2 / Metal Coatings


 Title:
Functionalization of hydroxyapatite-TiO2 coatings obtained by high velocity oxy-fuel

 Authors:
Sergi Dosta / Thermal Spray Centre (CPT) - Universitat de Barcelona, SPAIN
Hortensia Melero / Thermal Spray Centre (CPT) - Universitat de Barcelona, Spain
N Garcia-Giralt/ URFOA, IMIM, RETICEF, Spain
Javier Fernández/ Thermal Spray Centre (CPT) - Universitat de Barcelona, Spain
A Díez-Pérez/ URFOA, IMIM, RETICEF, Spain
Josep Maria Guilemany*/ Thermal Spray Centre (CPT) - Universitat de Barcelona, Spain

 Abstract:
Hydroxyapatite coatings have been used for many years to improve biological performance of bone implants, but several studies have drawn attention to the problems arising from high temperatures and the lack of mechanical properties. In this study, some hydroxyapatite-TiO2 HVOF coatings have been obtained and optimized. The TiO2 powder is added to the HAp to improve the mechanical properties. Different conditions have been tested to evaluate which are those with better biological properties. Wear resistance and toughness have been studied and the benefits of TiO2 improving toughness have been demonstrated. Viability and proliferation tests, as well as differentiation assays and morphology observation, are performed with human osteoblast cultures onto the studied coatings. The hydroxyapatite-TiO2 coatings maintain good cell viability and proliferation, especially the cases with higher amorphous phase amount and specific surface, and promote excellent differentiation, with a higher ALP amount for these cases than for polystyrene controls. Observation by SEM corroborates this excellent behavior. Collagen has been added to the starting raw materials and the benefits will also be discussed

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