|
| Abstract No.: |
|
Scheduled at:
|
Thursday, May 12, 2016, Room 3E 3:00 PM
Medical Industry
|
|
| Title: |
Strategies to develop bio-coating materials for new-generation of bone substitutes
|
|
| Authors: |
Kai Li / Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai
Xuebin Zheng* / Key Laboratory of Inorganic Coating Materials, Shanghai Institute of Ceramics, Chinese Academy of Sciences, China
|
|
| Abstract: |
Bio-coating technology is an effective approach to regulate the surface factors for bone substitute, and then strongly influence its cell interaction and thereby tissue integration at defect site. Hydroxyapatite and titanium coatings deposited by plasma spraying method are among the most widely applied coating materials for bone substitutes. However, there still remains considerable room for improvement in their comprehensive characteristics. In the present work, two methods have been employed to develop bio-coatings with promoted characteristics. Ti coating was surface modified via chemical or/and bio-chemical methods to obtain enhanced biological properties, while calcium silicate coatings possessing excellent bioactivity and strong connection to substrates were developed aiming to replace hydroxyapatite (a kind of calcium phosphate ceramics) coating. In vitro and in vivo examinations were carried out as well to verify the effectiveness of the research strategies.
|
|